Applied Pharmacokinetics & Pharmacodynamics: Principles of Therapeutic Drug MonitoringUsed by practitioners, educators, scientists, and students as a definitive reference source on pharmacokinetics, pharmacodynamics, and therapeutic drug monitoring, the fully updated Fourth Edition is a rigorous, yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and relevant pharmacotherapeutic data to optimize drug therapy for individual patients. |
Opinião das pessoas - Escrever uma crítica
Não foram encontradas quaisquer críticas nos locais habituais.
Índice
Dedication and Acknowledgment v Influence of Renal Function and Dialysis | 187 |
Special Pharmacokinetic | 213 |
General Principles of Clinical 11 Special Pharmacokinetic Considerations | 231 |
MONITORED DRUGS 257 | 239 |
Analysis of Pharmacokinetic Data for Glenn J Whelan and Stanley J Szefler | 285 |
Lalonde | 328 |
Influence of Protein Binding and Use of Pamela A MoiseBroder | 341 |
M Kashuba Joohyun J Park Adam M | 354 |
Application of Pharmacogenetic Principles | 410 |
Antiarrhythmic Drugs | 440 |
28 | 624 |
COxibs | 752 |
A Critical Assessment of | 839 |
Palavras e frases frequentes
absorption activity administration adults albumin allele altered aminoglycoside amiodarone amprenavir antibiotics Antimicrob Agents Chemother ARVs assay AUIC bioavailability Biopharm carbamazepine centrations changes Clin Pharmacokinet Clin Pharmacol Ther clinical cokinetics compared creatinine clearance CYP3A cytochrome decreased dialysis digoxin disease disopyramide dosage regimens dose drug concentrations drug interactions drug metabolism drug monitoring effect elimination Emax enzyme estimated evaluation excretion gentamicin half-life hepatic human increase indinavir infants Infect inhibition inhibitors intravenous kidney kinetics liver macokinetics measured metabolites method mg/L nelfinavir nephrotoxicity netics NRTIs obese oral patients peak Pediatr Phar Pharm pharmacodynamic pharmacoki pharmacologic phenobarbital phenytoin plasma concentrations plasma protein binding polymorphisms predicted procainamide propranolol ratio receptor renal failure renal function response result ritonavir saquinavir serum concentrations steady-state studies substrates theophylline Ther Drug Monit therapy tients tion tissue tobramycin toxicity tration unbound fraction valproic acid values vancomycin variability vitro Vmax volume of distribution zidovudine
Passagens conhecidas
Página 188 - Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo.
Página 462 - Echt DS, Liebson PR, Mitchell LB, et al Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.
Página 260 - Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease, N Engl J Med 1982:307: 652-659.
Página 263 - a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role, in particular, mast cells, eosinophils, T lymphocytes, macrophages, neutrophils, and epithelial cells. In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning.
Página 513 - A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial and systemic mycoses.
Página 462 - JA, et al. Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials. Circulation 1990;82:1106-1116.
Página 162 - The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.
Página 413 - Danner SA, Carr A, Leonard JM et al. A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease.
Página 188 - Willingham MC. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad Sci. USA.
Página 263 - In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the early morning. These episodes are usually associated with widespread but variable airflow obstruction that is often reversible either spontaneously or with treatment. The inflammation also causes bronchial hyperresponsiveness to a variety of stimuli (5).
Referências a este livro
Drug Benefits and Risks: International Textbook of Clinical Pharmacology Christoffel Jos van Boxtel,Budiono Santoso,I. Ralph Edwards Pré-visualização limitada - 2008 |
Informação bibliográfica
| Título | Applied Pharmacokinetics & Pharmacodynamics: Principles of Therapeutic Drug Monitoring |
| Editor | Michael E. Burton |
| Edição | ilustrada |
| Editora | Lippincott Williams & Wilkins, 2006 |
| ISBN | 0781744318, 9780781744317 |
| Número de páginas | 867 páginas |
| Exportar citação | BiBTeX EndNote RefMan |