Principles of Pharmacology: The Pathophysiologic Basis of Drug TherapyThis primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint. |
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Índice
XXXVI | 509 |
XXXVII | 529 |
XXXVIII | 547 |
XXXIX | 565 |
XL | 567 |
XLI | 585 |
XLII | 601 |
XLIII | 619 |
X | 91 |
XI | 107 |
XII | 109 |
XIII | 129 |
XIV | 145 |
XV | 161 |
XVII | 163 |
XVIII | 185 |
XIX | 207 |
XX | 225 |
XXI | 239 |
XXII | 263 |
XXIII | 283 |
XXIV | 305 |
XXV | 307 |
XXVI | 329 |
XXVII | 345 |
XXVIII | 367 |
XXIX | 387 |
XXX | 417 |
XXXI | 439 |
XXXII | 467 |
XXXIII | 469 |
XXXIV | 483 |
XXXV | 493 |
XLIV | 631 |
XLV | 651 |
XLVI | 675 |
XLVII | 701 |
XLVIII | 719 |
XLIX | 733 |
L | 735 |
LI | 747 |
LII | 769 |
LIII | 781 |
LIV | 795 |
LV | 811 |
LVI | 825 |
LVII | 841 |
LVIII | 849 |
LIX | 851 |
LX | 863 |
LXI | 885 |
LXII | 887 |
LXIII | 907 |
LXIV | 909 |
LXV | 917 |
LXVI | 935 |
Outras edições - Ver tudo
Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy David E. Golan Pré-visualização indisponível - 2005 |
Palavras e frases frequentes
ACE inhibitors acid action potential activity acute administration adrenal adrenergic adverse effects agents agonist androgen anesthesia anesthetic antiarrhythmic arrhythmias artery benzodiazepines binding block blood bone calcium cancer cardiac cause cells cellular channel blockers Chapter cholesterol chronic clinical concentration contractility coronary cortisol decrease depolarization diabetes digoxin disease diuretics dopamine dose endothelial enzyme estrogen excretion factors function GABA GABAA receptors glucocorticoid glutamate heart failure heparin hepatic hypertension inactivation increased inhibit insulin interactions intracellular levels liver mechanisms mediated membrane metabolism molecular molecules myocardial neurons neurotransmitter norepinephrine opioid oral osteoclasts oxide pain partial pressure pathway patients peptide peripheral Pharmacology pituitary gland plasma platelet postsynaptic protein receptor antagonists reduce release renal response result reuptake secretion seizures serotonin signaling smooth muscle sodium spinal stimulation subunit symptoms synaptic syndrome synthesis target therapeutic therapy thrombin thyroid hormone tion tissue toxicity transport treatment vascular vasodilation ventricular vesicles
Passagens conhecidas
Página 297 - Made a decision to turn our will and our lives over to the care of God as we understood Him.
Página 297 - Having had a spiritual awakening as the result of these steps, we tried to carry this message to alcoholics, and to practice these principles in all our affairs.
Página 285 - A maladaptive pattern of substance use, leading to clinically significant impairment or distress, as manifested by three (or more) of the following, occurring at any time in the same 12month period: 1) tolerance, as defined by either of the following: (a) a need for markedly increased amounts of the substance to achieve intoxication or desired effect, (b) markedly diminished effect with continued use of the same amount of the substance...
Página 201 - Report of the Quality Standards Subcommittee of the American Academy of Neurology.
Página 461 - Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT).
Página 285 - ... there is a persistent desire or unsuccessful efforts to cut down or control substance use (5) a great deal of time is spent in activities necessary to obtain the substance (eg, visiting multiple doctors or driving long distances), use the substance (eg, chain-smoking), or recover from its effects...
Página 195 - Two (or more) of the following, each present for a significant portion of time during a 1 -month period (or less if successfully treated): 1. Delusions 2. Hallucinations 3. Disorganized speech (eg, frequent derailment or incoherence) 4. Grossly disorganized or catatonic behavior 5. Negative symptoms (ie, affective flattening, alogia, or avolition) Note: Only one Criterion A symptom...
Página 297 - Sought through prayer and meditation to improve our conscious contact with God as we understood Him, praying only for knowledge of His will for us and the power to carry that out.
Página 285 - ... the substance use is continued despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance...
Página 195 - The symptoms are not due to the direct physiological effects of a substance (eg, a drug of abuse, a medication) or a general medical condition (eg, hypothyroidism).
Referências a este livro
Informação bibliográfica
| Título | Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy |
| Editor | David E. Golan |
| Edição | ilustrada |
| Editora | Lippincott Williams & Wilkins, 2008 |
| ISBN | 0781783550, 9780781783552 |
| Número de páginas | 985 páginas |
| Exportar citação | BiBTeX EndNote RefMan |