The Philosophy of Evidence-based MedicineJohn Wiley & Sons, 23/02/2011 - 244 páginas Evidence-based medicine (EBM) has become a required element of clinical practice, but it is critical for the healthcare community to understand the ongoing controversy surrounding EBM. Seeking to address questions raised by critics, The Philosophy of Evidence-based Medicine challenges the over dependency of EBM on randomized controlled trials. This book also explores EBM methodology and its relationship with other approaches used in medicine. |
Índice
The philosophy of evidencebased medicine | 3 |
What is EBM? | 10 |
What is good evidence for a clinical decision? | 24 |
Do randomization double masking and placebo | 31 |
when do observational studies | 39 |
types of restricted randomization | 60 |
problematic and misleading baseline measures | 80 |
Questioning the methodological superiority of placebo over active | 96 |
more detailed explanation of why the second assay | 114 |
A qualified defence of the EBM stance on mechanistic | 122 |
cases where mechanistic reasoning led to the adoption | 154 |
Moving EBM forward | 187 |
References | 193 |
225 | |
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Palavras e frases frequentes
absolute effect acupuncture antiarrhythmic drugs antidepressant argue assay sensitivity assay sensitivity argument believe benefit British Medical Journal cancer causal caused Chapter characteristic effects claim clinical expertise clinical judgment clinical trials clinically relevant clinicians Cochrane comparative clinical studies confounding factors control group control treatment controlled trials disease double blind double masking EBM hierarchy EBM movement EBM position EBM proponents EBM view effect size England Journal ofMedicine ethical evaluate evidence evidence-based medicine example experimental group experimental intervention experimental treatment expert judgment external validity flecainide Guyatt harmful Health involves mechanical rules mechanistic reasoning ment methodological mortality non-characteristic features non-inferiority trials observational studies pain participant and caregiver patient values patient-relevant outcomes PCTs pill placebo effect plausible confounders potential confounders predictions random allocation randomised randomized controlled trial randomized trials reduce role routine practice Russo and Williamson Sackett side-effects SSRIs statistical superiority systematic reviews therapeutic therapy tion values and circumstances