Genetics of Fitness and Physical Performance

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Human Kinetics, 1997 - 400 páginas
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Genetics of Fitness and Physical Performance is the first comprehensive reference on the role of the genes in influencing individual variation in fitness and performance.

This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes. Focusing on the interests of sport scientists, the authors provide insight into the significance of this research on nearly every aspect of the study of human physical activity.

The book presents the biological basis of heredity and explains the concepts and methods of genetic epidemiology and molecular biology that are necessary to understand this specialized field. With the rapid advances in molecular biology and the paradigms of human genetics, exercise scientists face a dynamic and vibrant new field. This book offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension by searching for single gene effects and identifying susceptibility genes.

The authors review the evidence on the role of the genes for human traits as it pertains to the exercise science field. And they explore the scientific, practical, and ethical issues that confront exercise scientists as progress is made in this field.

Genetics of Fitness and Physical Performance is vital reading for scholars in the field of exercise and sport science to understand how recent discoveries in genetics might shape their future research.

 

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Índice

The International Effort to Study the Human Genome
8
Chapter 2The Human Genome
15
The Structure of
23
The Human Gene
29
Regulation of Gene Expression
36
Mutation and Genetic Variation
42
Detection of Genetic Variation
49
Summary
55
GeneticEnvironment Interactions
187
Genetics and Regional Fat Distribution
202
Summary
209
Chapter 11Genetics and Skeletal Muscle
221
GenotypeTraining Interaction Effects in Skeletal Muscle
232
Chapter 12Genetics of Cardiorespiratory
243
Genetics of Pulmonary Function
250
Summary
259

Chapter 4Understanding the Methods
59
Detection of Major or SingleGene Effects
70
Detection of GenotypeEnvironment Interaction
78
References
84
HealthRelated Fitness
90
Summary
97
Genetic Effects in Health Status
104
Summary
115
Genetics of Resting Metabolic Rate and Thermic Effect of Food
121
Summary
128
Chapter 8Genetics of Dietary Intake
131
Taste Preferences
139
Chapter 9Genetics of Body Size
149
Genetics and Morphological Phenotypes
155
Summary
168
Life Span Gender and Population Variability
177
Chapter 13Genetics of Metabolic Fitness
267
Glucose and Insulin
275
Other Risk Factors
281
Summary
287
Chapter 14Genetics and Motor
299
Summary
307
Overview of Genetic Studies
321
Chapter 16Molecular Medicine
353
Implications for HealthRelated Fitness
359
Chapter 17Genes and HighPerformance
365
Summary
371
Considerations for the Exercise Scientist
377
Index
386
About the Authors
399
Direitos de autor

Palavras e frases frequentes

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Referências a este livro

Acerca do autor (1997)

Claude Bouchard,one of the world's leaders in the study of genetics and physical activity, is professor of exercise physiology and director of the Biology of Physical Activity Research Group at Université Laval in Sainte Foy, Quebec. He has an MSc in exercise physiology and a PhD in anthropological genetics.

For more than 20 years, Dr. Bouchard's research has focused on the genetic and molecular basis of human variation in body composition, physical fitness, and performance. This research has been supported by the Medical Research Council of Canada and other Canadian granting agencies as well as the U.S. National Institutes of Health.

Dr. Bouchard has authored or coauthored several books, including Growth, Maturation, and Physical Activity, and has published more than 500 professional and scientific papers. He received the Canadian Atherosclerosis Society Sandoz Award in 1996 at the Royal College of Physicians and Surgeons of Canada meeting. In 1997 Dr. Bouchard gave the J.B. Wolffe Lecture at American College of Sports Medicine Clinic meeting in Denver.

Dr. Bouchard is a Fellow of the American College of Sports Medicine and the American Society of Human Genetics. He recently has been elected as a foreign member of the Royal Academy of Medicine of Belgium.

Robert M. Malinais professor of physical education and exercise science at Michigan State University and director of the Institute for the Study of Youth Sports. Before assuming his position at MSU, Dr. Malina was professor of kinesiology and anthropology at the University of Texas at Austin for 28 years. He has a PhD in both physical education and physical anthropology and has done extensive research on the growth, maturation, and performance of children and youth in the United States and abroad.

Dr. Malina has served as president of the Human Biology Council and the American Academy of Physical Education, editor of the Yearbook of Physical Anthropology, and section editor for growth and development for the Research Quarterly for Exercise and Sport and the Exercise and Sport Sciences Review. He is editor-in-chief of the American Journal of Human Biology. Dr. Malina is coauthor of the book, Growth, Maturation, and Physical Activity, and has published more than 300 professional and scientific papers.

In 1989, Dr. Malina was awarded an honorary doctorate by the Institute of Physical Education, Faculty of Biomedical Sciences, Katholieke Universiteit Leuven, Belgium. He is a fellow of the American College of Sports Medicine, the American Association for the Advancement of Science, and the Human Biology Council, and an elected foreign member of the Polish Academy of Sciences.

Dr. Louis Pérusseis research scholar and associate professor in the Department of Physical Education at Université Laval in Sainte Foy, Quebec. He has an MSc and PhD in physical activity sciences from Université Laval. He has also completed postdoctoral work in human genetics at the University of Michigan at Ann Arbor.

Dr. Pérusse's research has focused on the genetic epidemiology of various determinants of physical fitness. He has published his findings in more than 75 scholarly journals and books, including several papers on the role of genes on body composition and blood pressure.

Dr. Pérusse is a member of the American College of Sports Medicine and the American Society of Human Genetics.

Informação bibliográfica

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TítuloGenetics of Fitness and Physical Performance
AutoresClaude Bouchard, Robert M. Malina, Louis Pérusse
EditoresRobert M. Malina, Louis Pérusse
Ediçãoilustrada
EditoraHuman Kinetics, 1997
ISBN0873229517, 9780873229517
Número de páginas400 páginas
  
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