Nature, Volume 450Sir Norman Lockyer Macmillan Journals Limited, 2007 |
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Página 119
... Jhdm2a- □ deficient mice exhibit post - meiotic chromatin condensation defects , and that JHDM2A directly binds to and controls the expression of transition nuclear protein 1 ( Tnp1 ) and protamine 1 ( Prml ) genes , the products of ...
... Jhdm2a- □ deficient mice exhibit post - meiotic chromatin condensation defects , and that JHDM2A directly binds to and controls the expression of transition nuclear protein 1 ( Tnp1 ) and protamine 1 ( Prml ) genes , the products of ...
Página 120
... Jhdm2a male mice were infertile ( data not shown ) . Histological analysis revealed multiple vacuolations in seminiferous tubules and fewer elongated spermatids in Jhdm2aGG testis ( Supplementary Fig . 3a ) . A detailed examination ...
... Jhdm2a male mice were infertile ( data not shown ) . Histological analysis revealed multiple vacuolations in seminiferous tubules and fewer elongated spermatids in Jhdm2aGG testis ( Supplementary Fig . 3a ) . A detailed examination ...
Página 122
... Jhdm2a might be a new candidate gene involved in these infertility syndromes . METHODS SUMMARY Generation of Jhdm2a mice . An ES clone with Jhdm2a gene - trap allele ( YHA186 ) was purchased from BayGenomics ( http://baygenomics.ucsf ...
... Jhdm2a might be a new candidate gene involved in these infertility syndromes . METHODS SUMMARY Generation of Jhdm2a mice . An ES clone with Jhdm2a gene - trap allele ( YHA186 ) was purchased from BayGenomics ( http://baygenomics.ucsf ...
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