Nature, Volume 434Sir Norman Lockyer Macmillan Journals Limited, 2005 |
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Página 109
... SCAN1 cells are unable to repair CPT - induced strand breaks rapidly . Consistent with this was our observation that CPT - induced breaks in SCAN1 cells failed to decline even if these cells were subsequently incubated in drug - free ...
... SCAN1 cells are unable to repair CPT - induced strand breaks rapidly . Consistent with this was our observation that CPT - induced breaks in SCAN1 cells failed to decline even if these cells were subsequently incubated in drug - free ...
Página 110
... SCAN1 cells preincubated with 5 μg ml ̄1 α - amanitin ( + & aman . ) , 0.2mM mimosine ( mim . ) , both ( mim . + aman . ) , or none ( -inhib . ) for 16 h . Residual transcription after a - amanitin was 7.1 ± 1.1 % ( mean ± s.e.m ) ...
... SCAN1 cells preincubated with 5 μg ml ̄1 α - amanitin ( + & aman . ) , 0.2mM mimosine ( mim . ) , both ( mim . + aman . ) , or none ( -inhib . ) for 16 h . Residual transcription after a - amanitin was 7.1 ± 1.1 % ( mean ± s.e.m ) ...
Página 112
... SCAN1 cells . a , Strand breaks were quantified in the indicated cells after mock treatment or treatment with H2O2 ( 150 μΜ , 10 min on ice ) , and after repair incubations for 30-60 min in drug - free medium . Asterisks denote ...
... SCAN1 cells . a , Strand breaks were quantified in the indicated cells after mock treatment or treatment with H2O2 ( 150 μΜ , 10 min on ice ) , and after repair incubations for 30-60 min in drug - free medium . Asterisks denote ...
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acid activity analysis antibody antigen apoptotic apoptotic cell applications areas assays binding biodiversity Biol biology cancer candidate CD8+ T cells Cell Biology centre Clb5 cluster complex cross-presentation cyclins dendritic detected drug electron emission encoded error experience expression function gap junctions GCRT gene genetic genome helpless CD8+ human HutP hydrogenosomes images indicated infection Institute interactions Izumo kinase laboratory levels ligand males measured mechanism mice mitochondrial molecular molecules monocytes mRNA mutant nanoparticles Nature nature publishing group Naturejobs observed ovalis peptide PGC-la PH domain PH-c phosphorylation Phys programme protein pyruvate quantum computing qubits radiolarites receptor region samples SCAN1 Science scientists sequence shown signalling siRNA SIRT1 sonoluminescence specific sperm structure substrates Supplementary Fig Supplementary Information Supplementary Table surface target TDP1 temperature transcription TRPC3 University wild-type XRCC1