Nature, Volume 434Sir Norman Lockyer Macmillan Journals Limited, 2005 |
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Página 35
... cyclins - three G1 cyclins ( Cln1-3 ) and six B - type cyclins ( Clb1-6 ) . These cyclins , in addition to activating Cdk1 , direct it towards distinct biological outcomes . But although cyclins had been implicated in substrate ...
... cyclins - three G1 cyclins ( Cln1-3 ) and six B - type cyclins ( Clb1-6 ) . These cyclins , in addition to activating Cdk1 , direct it towards distinct biological outcomes . But although cyclins had been implicated in substrate ...
Página 104
... cyclins . Different cyclins promote distinct cell - cycle events , but the molecular basis for these differences remains unclear12 . Here we compare the specificity of two budding yeast cyclins , the S - phase cyclin Clb5 and the M - phase ...
... cyclins . Different cyclins promote distinct cell - cycle events , but the molecular basis for these differences remains unclear12 . Here we compare the specificity of two budding yeast cyclins , the S - phase cyclin Clb5 and the M - phase ...
Página 107
... cyclins help to promote the correct timing of CDK substrate phosphorylation during the cell cycle . We argue that there is a fundamental advantage of this specificity over the quantitative model of cyclin function . In the quantitative ...
... cyclins help to promote the correct timing of CDK substrate phosphorylation during the cell cycle . We argue that there is a fundamental advantage of this specificity over the quantitative model of cyclin function . In the quantitative ...
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acid activity analysis antibody antigen apoptotic apoptotic cell applications areas assays binding biodiversity Biol biology cancer candidate CD8+ T cells Cell Biology centre Clb5 cluster complex cross-presentation cyclins dendritic detected drug electron emission encoded error experience expression function gap junctions GCRT gene genetic genome helpless CD8+ human HutP hydrogenosomes images indicated infection Institute interactions Izumo kinase laboratory levels ligand males measured mechanism mice mitochondrial molecular molecules monocytes mRNA mutant nanoparticles Nature nature publishing group Naturejobs observed ovalis peptide PGC-la PH domain PH-c phosphorylation Phys programme protein pyruvate quantum computing qubits radiolarites receptor region samples SCAN1 Science scientists sequence shown signalling siRNA SIRT1 sonoluminescence specific sperm structure substrates Supplementary Fig Supplementary Information Supplementary Table surface target TDP1 temperature transcription TRPC3 University wild-type XRCC1