Nature, Volume 434Sir Norman Lockyer Macmillan Journals Limited, 2005 |
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Página 89
... helpless CD8 + T cells ( Fig . 2a ) , cells which subsequently failed to expand ( data not shown ) . Both purified helped and helpless CD8 + T cells upregulated mRNA for TNF and TRAIL receptor DR5 ( TRAIL - R2 ) 9-11 following ...
... helpless CD8 + T cells ( Fig . 2a ) , cells which subsequently failed to expand ( data not shown ) . Both purified helped and helpless CD8 + T cells upregulated mRNA for TNF and TRAIL receptor DR5 ( TRAIL - R2 ) 9-11 following ...
Página 90
... helpless and helped CD8 + T cells expressed DR5 following secondary antigenic stimulation ( Figs 2 and 3 ) , but only the helped CD8 + T cells upregulated FLIP mRNA , encoding a protein that can potentially inhibit TRAIL - mediated ...
... helpless and helped CD8 + T cells expressed DR5 following secondary antigenic stimulation ( Figs 2 and 3 ) , but only the helped CD8 + T cells upregulated FLIP mRNA , encoding a protein that can potentially inhibit TRAIL - mediated ...
Página 91
... CD8 + T cells . a , mRNA levels for Bcl - 2 , Bcl - xL , FasL , Trail , DR5 and FLIP were determined by real - time RT - PCR at different time points following in vitro GP33-41 - peptide restimulation of purified CD8 ... helpless CD8 + T ...
... CD8 + T cells . a , mRNA levels for Bcl - 2 , Bcl - xL , FasL , Trail , DR5 and FLIP were determined by real - time RT - PCR at different time points following in vitro GP33-41 - peptide restimulation of purified CD8 ... helpless CD8 + T ...
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acid activity analysis antibody antigen apoptotic apoptotic cell applications areas assays binding biodiversity Biol biology cancer candidate CD8+ T cells Cell Biology centre Clb5 cluster complex cross-presentation cyclins dendritic detected drug electron emission encoded error experience expression function gap junctions GCRT gene genetic genome helpless CD8+ human HutP hydrogenosomes images indicated infection Institute interactions Izumo kinase laboratory levels ligand males measured mechanism mice mitochondrial molecular molecules monocytes mRNA mutant nanoparticles Nature nature publishing group Naturejobs observed ovalis peptide PGC-la PH domain PH-c phosphorylation Phys programme protein pyruvate quantum computing qubits radiolarites receptor region samples SCAN1 Science scientists sequence shown signalling siRNA SIRT1 sonoluminescence specific sperm structure substrates Supplementary Fig Supplementary Information Supplementary Table surface target TDP1 temperature transcription TRPC3 University wild-type XRCC1