Nature, Volume 434Sir Norman Lockyer Macmillan Journals Limited, 2005 |
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Página 342
... miRNAs ( encoded by 222 miRNA genes ) listed in the current registry28 . Roughly 43.5 % of the known miRNAs can match through Watson - Crick pairing to the highly conserved 8 - mer motifs ( versus 2 % for an equal number of random 8 ...
... miRNAs ( encoded by 222 miRNA genes ) listed in the current registry28 . Roughly 43.5 % of the known miRNAs can match through Watson - Crick pairing to the highly conserved 8 - mer motifs ( versus 2 % for an equal number of random 8 ...
Página 343
... miRNA genes . Moreover , there are likely to be many additional miRNAs inasmuch as our approach was only designed to find those containing a conserved 8 - mer and thus only detects one - half of known miRNAs . This challenges a recent ...
... miRNA genes . Moreover , there are likely to be many additional miRNAs inasmuch as our approach was only designed to find those containing a conserved 8 - mer and thus only detects one - half of known miRNAs . This challenges a recent ...
Página 344
... miRNA target sites in the human genome that are not conserved across all mammals ; it Table 2 Top 50 conserved 8 - mers in 3 ' UTRs and corresponding miRNAs No. Motif Conservation rate MiRNA * GTGCAATA 0.55 GTGCCTTA 0.54 3 CTACCTCA 0.53 ...
... miRNA target sites in the human genome that are not conserved across all mammals ; it Table 2 Top 50 conserved 8 - mers in 3 ' UTRs and corresponding miRNAs No. Motif Conservation rate MiRNA * GTGCAATA 0.55 GTGCCTTA 0.54 3 CTACCTCA 0.53 ...
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