Nature, Volume 456Sir Norman Lockyer Macmillan Journals Limited, 2008 |
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Página 58
... Genome Sequencing Consortium . Finishing the euchromatic sequence of the human genome . Nature 431 , 931-945 ( 2004 ) . Levy , S. et al . The diploid genome sequence of an individual human . PLoS Biol . 5 , e254 ( 2007 ) . 3. Margulies ...
... Genome Sequencing Consortium . Finishing the euchromatic sequence of the human genome . Nature 431 , 931-945 ( 2004 ) . Levy , S. et al . The diploid genome sequence of an individual human . PLoS Biol . 5 , e254 ( 2007 ) . 3. Margulies ...
Página 67
... genome of a single AML patient and the matched normal genome ( derived from a skin biopsy ) of the same patient . After alignment to the human reference genome , sequence variants were discovered in the tumour genome and compared to the ...
... genome of a single AML patient and the matched normal genome ( derived from a skin biopsy ) of the same patient . After alignment to the human reference genome , sequence variants were discovered in the tumour genome and compared to the ...
Página 71
... genome sequencing , there are several advan- tages to the approach we used : ( 1 ) coverage models for whole- genome libraries are at present better understood than for cDNA libraries , where transcript abundance can vary over many ...
... genome sequencing , there are several advan- tages to the approach we used : ( 1 ) coverage models for whole- genome libraries are at present better understood than for cDNA libraries , where transcript abundance can vary over many ...
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