Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedElsevier, 06/06/2003 - 166 páginas This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
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Página 131
... Dose, time, and effects 149 Dose matters 150 Murphy's contribution 150 Atomic radiation The Hiroshima and Nagasaki bombs 150 What these studies found 150 Microcephaly and mental retardation 151 Other radiation sources 151 Rubella ...
... Dose, time, and effects 149 Dose matters 150 Murphy's contribution 150 Atomic radiation The Hiroshima and Nagasaki bombs 150 What these studies found 150 Microcephaly and mental retardation 151 Other radiation sources 151 Rubella ...
Página 132
... Dose- and time-response relations 170 Animal studies with thalidomide 171 Postscript: was anyone to blame? 172 The future? 172 TESTING FOR TERATOGENICITY Proposals for drug testing 173 The procedure 174 The consequence 174 The dose ...
... Dose- and time-response relations 170 Animal studies with thalidomide 171 Postscript: was anyone to blame? 172 The future? 172 TESTING FOR TERATOGENICITY Proposals for drug testing 173 The procedure 174 The consequence 174 The dose ...
Página 133
... dosage differences 213 Further teratologic threat: etretinate 213 Acitretin 214 Dose—response relations 214 Topical tretinoin use 214 Anticonvulsant drugs Introduction: the falling sickness 215 Therapy of epilepsy; fetal consequences ...
... dosage differences 213 Further teratologic threat: etretinate 213 Acitretin 214 Dose—response relations 214 Topical tretinoin use 214 Anticonvulsant drugs Introduction: the falling sickness 215 Therapy of epilepsy; fetal consequences ...
Página 148
... dose accurately, and thus could only poorly relate general and specific tissue susceptibility to dosage and prenatal stage. This was overcome in time, leading to ever more precise understanding of these relations (Job et al., 1935 ...
... dose accurately, and thus could only poorly relate general and specific tissue susceptibility to dosage and prenatal stage. This was overcome in time, leading to ever more precise understanding of these relations (Job et al., 1935 ...
Página 149
... Dose, time, and effects. Two attempts have been made to relate irradiation dose, gestation age irradiated, and fetal outcome in humans. The first, by drawing developmental parallels between human and animal gestational intervals, so far ...
... Dose, time, and effects. Two attempts have been made to relate irradiation dose, gestation age irradiated, and fetal outcome in humans. The first, by drawing developmental parallels between human and animal gestational intervals, so far ...
Índice
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
167 | |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
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Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Pré-visualização limitada - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Pré-visualização indisponível - 2003 |
Palavras e frases frequentes
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