Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedElsevier, 06/06/2003 - 166 páginas This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
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Página 132
... THALIDOMIDE The event 167 The thalidomide syndrome 168 The revelation 168 Thalidomide: safety and sales 169 Toxicity in adults 169 Thalidomide in the USA 169 Thalidomide's teratogenic mechanism 170 Dose- and time-response relations 170 ...
... THALIDOMIDE The event 167 The thalidomide syndrome 168 The revelation 168 Thalidomide: safety and sales 169 Toxicity in adults 169 Thalidomide in the USA 169 Thalidomide's teratogenic mechanism 170 Dose- and time-response relations 170 ...
Página 134
... thalidomide left a scar yet raw. For still others— clinicians, academics, experimentalists—the upsurge in the interest in fetal maldevelopment is at a different level, and their pursuits are broad, taking external agents as but one of ...
... thalidomide left a scar yet raw. For still others— clinicians, academics, experimentalists—the upsurge in the interest in fetal maldevelopment is at a different level, and their pursuits are broad, taking external agents as but one of ...
Página 139
... thalidomide to be avoided or rendered harmless, much still remains to be learned, especially about endogenous causes of maldevelopment and their prevention. 3.2. Classification by cause The difficulties of discovering the causes of ...
... thalidomide to be avoided or rendered harmless, much still remains to be learned, especially about endogenous causes of maldevelopment and their prevention. 3.2. Classification by cause The difficulties of discovering the causes of ...
Página 148
... thalidomide (Lenz, 1962; McBride, 1961a,b). The main function of registries supposedly is to alert to impending malformation epidemics and hopefully to avert them, purposes they hope to achieve by monitoring malformation births through ...
... thalidomide (Lenz, 1962; McBride, 1961a,b). The main function of registries supposedly is to alert to impending malformation epidemics and hopefully to avert them, purposes they hope to achieve by monitoring malformation births through ...
Página 167
... Thalidomide 9. 1. The event An event the year following the formation of the Teratology Society which shook scientific circles, government officials, the pharmaceutical industry, and the public worldwide made the H. Kalter ...
... Thalidomide 9. 1. The event An event the year following the formation of the Teratology Society which shook scientific circles, government officials, the pharmaceutical industry, and the public worldwide made the H. Kalter ...
Índice
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
167 | |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
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Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Pré-visualização limitada - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Pré-visualização indisponível - 2003 |
Palavras e frases frequentes
abnormalities abortion agents alcohol animals anomalies appeared associated birth birth defects cause Child cleft congenital malformations considered consumption death defects deficiency diabetic discussed disease dose drinking drug early editors effects embryos environmental especially et al evidence examined experimental exposed exposure fact factors fetal findings folic acid frequency Genet given growth Health hospital human important included increased indicated induced infants Kalter known Lancet later less levels Love Canal major maternal means mental minor mothers neural tube neural tube defects normal noted occurred offspring origin outcome pattern Pediatr perhaps period population possible pregnancy prenatal present prevalence prospective question records reduced relation relatively reported retardation risk rubella seems severe specific spina bifida supplementation syndrome teratogenic Teratology testing thalidomide tion usually various vitamin Warkany weeks women York