NatureSir Norman Lockyer Macmillan Journals Limited, 2007 |
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Página 230
... genipin increases mitochondrial mem- brane potential , which then increases ATP levels and closes KATP channels , thereby stimulating insulin secretion . These actions of gen- ipin are all secondary to inhibition of UCP2 , as they are ...
... genipin increases mitochondrial mem- brane potential , which then increases ATP levels and closes KATP channels , thereby stimulating insulin secretion . These actions of gen- ipin are all secondary to inhibition of UCP2 , as they are ...
Página 231
... genipin . There was a high degree of concordance between glucose sensing and activation by genipin - if a neuron was activated by glucose , it was usually excited by genipin ( Fig . 3a ) , and if a neuron was glucose - insensitive ...
... genipin . There was a high degree of concordance between glucose sensing and activation by genipin - if a neuron was activated by glucose , it was usually excited by genipin ( Fig . 3a ) , and if a neuron was glucose - insensitive ...
Página 232
... genipin ( 20 μM ) or leptin ( 100 nM ) during recording . For aMSH release assays , 2 - mm thick hypothalamic slices were incubated in artificial cerebrospinal fluid ( aCSF ) containing 8 mM glucose ( baseline ) for 45 min , followed by ...
... genipin ( 20 μM ) or leptin ( 100 nM ) during recording . For aMSH release assays , 2 - mm thick hypothalamic slices were incubated in artificial cerebrospinal fluid ( aCSF ) containing 8 mM glucose ( baseline ) for 45 min , followed by ...
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Immunology | 35 |
Preclinical research studies | 113 |
An essential resource for immunology researchers | 374 |
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