Nature, Volume 428Sir Norman Lockyer Macmillan Journals Limited, 2004 |
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Página 79
... cyclin E protein ( Fig . 2d ) and a higher percentage of micronuclei formation as compared with parental cells ... Cyclin E a - Tubulin Cyclin E -1- RT HSG HCT116 DLD - 1 + / + + / + + / + - / - - / - + / + - / - - / - hCDC4 genotype ...
... cyclin E protein ( Fig . 2d ) and a higher percentage of micronuclei formation as compared with parental cells ... Cyclin E a - Tubulin Cyclin E -1- RT HSG HCT116 DLD - 1 + / + + / + + / + - / - - / - + / + - / - - / - hCDC4 genotype ...
Página 80
... Cyclin E is the only known target of the ubiquitin ligase activity of hCDC4 . To determine whether the increased abundance of cyclin E was sufficient to reproduce the phenotype observed on inactivation of hCDC4 , we overexpressed cyclin ...
... Cyclin E is the only known target of the ubiquitin ligase activity of hCDC4 . To determine whether the increased abundance of cyclin E was sufficient to reproduce the phenotype observed on inactivation of hCDC4 , we overexpressed cyclin ...
Página 191
... cyclin A and cyclin B and the disappearance of phosphorylation on Ser 10 of histone H3 ( Fig . 2a ) . By contrast , silencing of Cdc20 delayed mitotic exit by about 1h ( data not shown ) . Second , cyclin A and cyclin B are normally ...
... cyclin A and cyclin B and the disappearance of phosphorylation on Ser 10 of histone H3 ( Fig . 2a ) . By contrast , silencing of Cdc20 delayed mitotic exit by about 1h ( data not shown ) . Second , cyclin A and cyclin B are normally ...
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of genetically modified grain | 8 |
Just | 14 |
Medical editors urged to accept ethical code | 17 |
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