Handbook of Models for Human AgingP. Michael Conn Elsevier, 28/04/2011 - 1075 páginas The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues.
|
No interior do livro
Resultados 1-5 de 83
Página x
... Culture as Models for the Impact of Chronic Antigenic Stress in Aging................................................781 Graham Pawelec, Erminia Mariani, Rafael Solana, Rosalyn Forsey, Anis Larbi, Simone Neri, Olga Dela Rosa, Yvonne ...
... Culture as Models for the Impact of Chronic Antigenic Stress in Aging................................................781 Graham Pawelec, Erminia Mariani, Rafael Solana, Rosalyn Forsey, Anis Larbi, Simone Neri, Olga Dela Rosa, Yvonne ...
Página 29
... culture. Aging Cell 2, 287–294. Chiu B.C., Shang X., Frait K.A., Hu J.S., Komuniecki E., Miller R.A., and Chensue S.W. (2002). Differential effects of ageing on cytokine and chemokine responses during type-1 (mycobacterial) and type-2 ...
... culture. Aging Cell 2, 287–294. Chiu B.C., Shang X., Frait K.A., Hu J.S., Komuniecki E., Miller R.A., and Chensue S.W. (2002). Differential effects of ageing on cytokine and chemokine responses during type-1 (mycobacterial) and type-2 ...
Página 33
... culture protocols for analyzing the effect of chronic antigenic stimulation on primary T cells from young adult donors has led to the identification of multiple characteristics of the terminal stage of replicative senescence in this ...
... culture protocols for analyzing the effect of chronic antigenic stimulation on primary T cells from young adult donors has led to the identification of multiple characteristics of the terminal stage of replicative senescence in this ...
Página 34
... culture data on other cell types, a preliminary estimate would suggest that the degree of proliferation achievable by each T cell is so large that the finite replicative ... Cultures of Human T Cells SUMMARY OF THE CULTURE 34 Rita B. Effros.
... culture data on other cell types, a preliminary estimate would suggest that the degree of proliferation achievable by each T cell is so large that the finite replicative ... Cultures of Human T Cells SUMMARY OF THE CULTURE 34 Rita B. Effros.
Página 35
P. Michael Conn. Primary. Cultures. of. Human. T. Cells. SUMMARY OF THE CULTURE PROTOCOL Our cell culture studies have focused on the analysis of the CD8þ T cell subset, the cell type responsible for controlling viral infections, which are ...
P. Michael Conn. Primary. Cultures. of. Human. T. Cells. SUMMARY OF THE CULTURE PROTOCOL Our cell culture studies have focused on the analysis of the CD8þ T cell subset, the cell type responsible for controlling viral infections, which are ...
Outras edições - Ver tudo
Palavras e frases frequentes
adult age-related aged rats aging process aging research Alzheimer’s disease amyloid analysis animal models apoptosis Austad bats behavioral Biol biology brain caloric restriction cancer cellular changes chromosome cognitive colony compared correlation cortex culture decline decrease dogs Drosophila melanogaster dwarf mice effects elegans embryos factors females Figure flies function Gavrilov gene expression genetic genome Gerontol glucose GnRH Gompertz growth hippocampal honeybee hormone human aging immune impaired increase individual infection insulin laboratory levels lifespan long-lived longevity mammalian mammals mechanisms metabolic methods microarray mitochondrial molecular mortality mouse mtDNA mutations neurons normal oocytes organisms oxidative damage oxidative stress pathway phenotype physiological place cells population potential primates protein proteomic ratti receptor regulation replicative reproductive response rhesus monkeys rodents role senescence Sir2 span spatial species strains studies telomerase telomerase activity telomere telomere length tion tissue transgenic yeast zebrafish