Handbook of Models for Human AgingP. Michael Conn Elsevier, 28/04/2011 - 1075 páginas The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues.
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... rhesus monkeys and humans. These studies are ongoing and provide a lively subtext to the lifespan extension literature, as CR is to date the only intervention that reliably increases lifespan in mammals (Weindruch et al., 1982; Yu et al ...
... rhesus monkeys and humans. These studies are ongoing and provide a lively subtext to the lifespan extension literature, as CR is to date the only intervention that reliably increases lifespan in mammals (Weindruch et al., 1982; Yu et al ...
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... primates is unparalleled. They must be studied. The NIA has sought to help make aged rhesus macaques available to the research community by supporting their maintenance at several primate research facilities around the United States ...
... primates is unparalleled. They must be studied. The NIA has sought to help make aged rhesus macaques available to the research community by supporting their maintenance at several primate research facilities around the United States ...
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... rhesus monkeys. Exp. Gerontol. 38, 35–46. McCarter, R., Shimokawa, A., Ikeno, Y., Higami, Y., Hubbard, G., Yu, B.P., and McMahan,C. (1997). Physical activity as a factor in the action of dietary restriction on aging: Effects in Fischer ...
... rhesus monkeys. Exp. Gerontol. 38, 35–46. McCarter, R., Shimokawa, A., Ikeno, Y., Higami, Y., Hubbard, G., Yu, B.P., and McMahan,C. (1997). Physical activity as a factor in the action of dietary restriction on aging: Effects in Fischer ...
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... rhesus monkeys: Relevance to human health interventions. Science 305, 1423–1426. Sacher, G.A., and Hart, R.W. (1978). Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed ...
... rhesus monkeys: Relevance to human health interventions. Science 305, 1423–1426. Sacher, G.A., and Hart, R.W. (1978). Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed ...
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... monkeys (family: Cercopithecidae), which are generally shorter-lived than apes. Two species of Old World Figure 2.2 ... rhesus monkeys and baboons. Both appear to age considerably faster than humans and great apes, making them ...
... monkeys (family: Cercopithecidae), which are generally shorter-lived than apes. Two species of Old World Figure 2.2 ... rhesus monkeys and baboons. Both appear to age considerably faster than humans and great apes, making them ...
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adult age-related aged rats aging process aging research Alzheimer’s disease amyloid analysis animal models apoptosis Austad bats behavioral Biol biology brain caloric restriction cancer cellular changes chromosome cognitive colony compared correlation cortex culture decline decrease dogs Drosophila melanogaster dwarf mice effects elegans embryos factors females Figure flies function Gavrilov gene expression genetic genome Gerontol glucose GnRH Gompertz growth hippocampal honeybee hormone human aging immune impaired increase individual infection insulin laboratory levels lifespan long-lived longevity mammalian mammals mechanisms metabolic methods microarray mitochondrial molecular mortality mouse mtDNA mutations neurons normal oocytes organisms oxidative damage oxidative stress pathway phenotype physiological place cells population potential primates protein proteomic ratti receptor regulation replicative reproductive response rhesus monkeys rodents role senescence Sir2 span spatial species strains studies telomerase telomerase activity telomere telomere length tion tissue transgenic yeast zebrafish