Integrated Molecular and Cellular Biophysics

Capa
Springer Science & Business Media, 17/06/2008 - 250 páginas
Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.

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Páginas seleccionadas

Índice

The Molecular Basis of Life
7
The Composition and Architecture of the Cell
39
Structure and Physical Properties
73
Substance Transport Across Membranes
101
Reaction Diffusion and Dimensionality
123
Electrophysiology and Excitability
147
Structure and Function of Molecular Machines
173
ProteinProtein Interactions
195
Answers to Selected Quizzes
219
Appendix
227
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Página 38 - The Hydrophobic Effect: Formation of Micelles and Biological Membranes', Wiley, New York, 1980.
Página 171 - Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties.
Página 38 - Theory of Self-Assembly of Hydrocarbon Amphiphiles into Micelles and Bilayers, J.
Página 99 - The complex conductivity of a suspension of stratified particles of spherical cylindrical form.
Página 171 - ... Colloid Science, Vol. I, Irreversible Systems, Hydrophobic Colloids. Elsevier Publishing Co. New York. LING, GN & RW GERARD. 1949. The normal membrane potential of frog sartorius fibers. J. Cell. Comp. Physiol. 34: 382-396. MAC!NNES, DA 1939. The Principles of Electrochemistry. Reinhold Publishing Corp. New York. MARMONT, G. 1949. Studies on the axon membrane. I. A new method. J. Cell. Comp. Physiol. 34: 351-382. MAURO, A. 1954. Electrochemical potential difference of chloride ion in the giant...
Página 201 - Pop«,(R f jUsin0 + |cos0| (Anisotropy scattering) (43) (44) where y is the quantum efficiency of the phototube, h is Planck's constant, c is the speed of light in vacuum, and n is the solution refractive index.

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